METABOLISM OF PHOSPHOLIPIDES BY BACTERIAL ENZYMES

Metabolism of phospholipides by bacterial enzymes.

The Degradation of Heparin by Bacterial Enzymes

Extracts of acetone powders of Flavobacterium heparinum which have been adapted to heparin catalyze a rather extensive degradation of this mucopolysaccharide. This ‘Lheparinase” activity is due to the presence in the extract of a sulfamidase, a sulfesterase, and at least one glycosidase (1, 2). Such extracts also catalyze the hydrolysis of hyaluronic acid and chondroitin sulfate. This paper com...

Metabolism of cytosine, thymine, uracil, and barbituric acid by bacterial enzymes.

Early stud& with pyrimidines administered t.o animals established the fact that, these compounds arc metabolized (3, 4). Present concepts of the pathways of pyrimidine metabolism stem largely from the work of Cerecedo (4), in which he measured the changes in the urinary excretion of urea after feeding pyrimidines and related subst.ances. On the basis of these studies, he proposed an init.ial ox...

On the absorption of phospholipides.

It is generally assumed that phospholipides are hydrolyzed in the gastrointestinal tract and absorbed in the form of their constituent parts. Indeed, enzymes capable of splitting phospholipides have been found in many tissues, including intestinal mucosa, pancreas, and pancreatic juice. The earlier findings have been reviewed by Belfanti, Contardi, and Ercoli (2), and additional evidence on thi...

Enzymes of Polynucleotide Metabolism

The latest memoir of the Society for Endocrinology presents the papers and discussions of a 1958 symposium on selected aspects of comparative and human sex morphology. It is gratifying that discussions of bacteria and invertebrate forms are included. Several authors examine the important question of genetic and hormonal controls of sex differentiation. The possibility of regulating the sex rati...